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Our proprietary strains support GLP-1 production naturally
GLP-1 Probiotic is formulated with bacterial strains that boost this process naturally.*
1
As you eat, metabolic processes are triggered in your body
2
In the gut microbiome, the beneficial bacteria–such as Akkermansia and Butyricum–convert the fiber in your food into butyrate, and Akkermansia secretes a protein called p9
3
Butyrate and p9 stimulate GLP-1, the hormone that tells your pancreas to produce insulin, slowing down the emptying of your stomach
4
This sends a signal to your brain that you’re full, reducing your appetite, helping to maintain a healthy weight
*Based on preclinical studies
Our strains deserve a spotlight
Precision matters. Meet the powerful ingredients behind Pendulum’s next-generation probiotics.
Akkermansia muciniphila
A highly targeted strain that can only be found in Pendulum products. Akkermansia is essential for gut health. It helps strengthen the gut lining, improves digestive health, and helps manage a healthy weight.
Clostridium butyricum
Naturally found in the human gastrointestinal tract, this strain is named for its ability to produce high amounts of the short-chain fatty acid butyrate. It has been associated with digestion support and immune health.
Clostridium beijerinckii
This novel strain produces the short-chain fatty acid butyrate, which helps the body process sugar and nourish the lining of the gut.
Anaerobutyricum hallii
This is another strain known to produce the short-chain fatty acid butyrate, to help the body process sugar and nourish the lining of the gut.
Bifidobacterium infantis
This strain breaks down a range of foods and produces the intermediate molecules that are used by the three butyrate-producing strains we have. It also helps maintain a healthy gastrointestinal tract and alleviates digestive issues.
State of the art delivery capsule
Our probiotics are encased in a plant-based, acid-resistant, delayed release capsule, so that the strains get through the stomach acid and to the gut microbiome where it can do its job.
Live vs pasteurized bacteria
Watch the full Q&A webinar on live vs. pasteurized with Dr. Colleen Cutcliffe, PhD
Webinar content is for educational purposes only
Webinar content is for educational purposes only
Breaks down
fibers in the gut
fibers in the gut
Colonizes
the gut
the gut
Produces postbiotics
in the colon
in the colon
Associated with
Contains beneficial
bacterial components
bacterial components
Live
Akkermansia
Akkermansia
Pasteurized
Akkermansia
Akkermansia
Live Akkermansia: the gold standard in probiotic formulation
Only live Akkermansia can consume mucin and
stimulate goblet cells to produce new mucin to
maintain gut barrier integrity.
Only live Akkermansia can work with consumed fiber
and polyphenols to colonize the gut.
The majority of studies that identify health-promoting benefits of Akkermansia in humans have looked at live bacteria; therefore, many of the mechanisms observed in live Akkermansia are not transferable to pasteurized bacterium.
Pasteurized/dead Akkermansia: limited, one-time benefit
Pasteurized Akkermansia does not enable the mucin regulation process for maintaining gut barrier integrity.
Pasteurized Akkermansia does not provide the important interactions and molecules produced through the synergy of diet and live beneficial microorganisms.
Amuc_1100, an outer-membrane protein of Akkermansia, is one of the only extracellular vesicles (EVs) mentioned in studies observing pasteurized Akkermansia; however, it retains only partial stability with pasteurization. Other heat sensitive enzymes found in live Akkermansia are not functional post pasteurization.
Find the perfect probiotic for your patients
Find the perfect probiotic for your patients
Help curb appetite and cravings
GLP-1 Probiotic
GLP-1 Probiotic
- 91% reported reduced overall food cravings*
- Enhances natural GLP-1 production**
- Helps maintain a healthy weight
*Based on preclinical studies
** Based on a consumer survey of 274 people
Improve metabolism*
Metabolic Daily
Metabolic Daily
- Helps metabolize sugars & carbs*
- Converts food into energy more efficiently*
- Sustains energy levels
*Based on preclinical studies
Replenish keystone strain
Akkermansia
Akkermansia
- Improves gut health
- Strengthens gut lining*
- Reduces gut permeability*
*Based on preclinical studies
Lower glucose spikes & A1C
Glucose Control
Glucose Control
- Reduces blood sugar
- Clinically-proven
- Highest potency formulation
Alleviate GI discomfort
Butyricum
Butyricum
- Relieves occasional gas
- Makes you more regular
- Helps with diarrhea & constipation
Boost probiotics with antioxidants
Polyphenol Booster
Polyphenol Booster
- Stimulates cells for healthy aging
- Supports heart health
- Boosts Akkermansia levels for gut health*
*In vitro testing has found that polyphenols feed and boost Akkermansia, a keystone beneficial strain.
Introducing
Doctor-formulated probiotics exclusively on
Hear from world-class healthcare providers and institutions
Top doctors and researchers recognize the potential of Pendulum's novel strains. Our prestigious advisors hold leadership positions at leading research institutions such as Johns Hopkins, Cornell, UCLA, Mayo Clinic, and Stanford Medicine.
Together, we're advancing the world's understanding of health and the microbiome.
Kara Fitzgerald, ND, IFMCP
Mark Hyman, MD
Melina Jampolis, MD
Stay informed on microbiome research and access resources for patients and providers
Learn more about how we can help you grow your practice with Pendulum products
Schedule a chat with our Senior Healthcare Account Manager, Christina O'Connor, RD. Schedule Now